diff --git a/examples/cog-blob.html b/examples/cog-blob.html
new file mode 100644
index 0000000000..f876e635ce
--- /dev/null
+++ b/examples/cog-blob.html
@@ -0,0 +1,10 @@
+---
+layout: example.html
+title: Cloud Optimized GeoTIFF (COG) from a Blob
+shortdesc: Rendering a COG as a tiled layer from a Blob.
+docs: >
+  Tiled data from a Cloud Optimized GeoTIFF (COG) can be rendered as a layer.  In this
+  example, a single 3-band GeoTIFF is used to render RGB data from a Blob.
+tags: "cog"
+---
+<div id="map" class="map"></div>
diff --git a/examples/cog-blob.js b/examples/cog-blob.js
new file mode 100644
index 0000000000..0d16dd0273
--- /dev/null
+++ b/examples/cog-blob.js
@@ -0,0 +1,28 @@
+import GeoTIFF from '../src/ol/source/GeoTIFF.js';
+import Map from '../src/ol/Map.js';
+import TileLayer from '../src/ol/layer/WebGLTile.js';
+
+fetch('data/example.tif')
+  .then((response) => response.blob())
+  .then((blob) => {
+    const source = new GeoTIFF({
+      sources: [
+        {
+          blob: blob,
+        },
+      ],
+    });
+
+    const map = new Map({
+      target: 'map',
+      layers: [
+        new TileLayer({
+          source: source,
+        }),
+      ],
+      view: source.getView().then((viewConfig) => {
+        viewConfig.showFullExtent = true;
+        return viewConfig;
+      }),
+    });
+  });
diff --git a/examples/data/example.tif b/examples/data/example.tif
new file mode 100644
index 0000000000..6ee9b0e226
Binary files /dev/null and b/examples/data/example.tif differ
diff --git a/examples/resources/common.js b/examples/resources/common.js
index d7b4db7682..c210631f7c 100644
--- a/examples/resources/common.js
+++ b/examples/resources/common.js
@@ -9,7 +9,7 @@
 
   function fetchResource(resource) {
     return new Promise(function (resolve, reject) {
-      const isImage = /\.(png|jpe?g|gif|tiff|svg|kmz)$/.test(resource);
+      const isImage = /\.(png|jpe?g|gif|tiff?|svg|kmz)$/.test(resource);
       if (isImage) {
         resolve ({
           isBinary: true,
diff --git a/src/ol/source/GeoTIFF.js b/src/ol/source/GeoTIFF.js
index 2188a297b1..c252877be9 100644
--- a/src/ol/source/GeoTIFF.js
+++ b/src/ol/source/GeoTIFF.js
@@ -4,7 +4,12 @@
 import DataTile from './DataTile.js';
 import State from './State.js';
 import TileGrid from '../tilegrid/TileGrid.js';
-import {Pool, fromUrl as tiffFromUrl, fromUrls as tiffFromUrls} from 'geotiff';
+import {
+  Pool,
+  fromBlob as tiffFromBlob,
+  fromUrl as tiffFromUrl,
+  fromUrls as tiffFromUrls,
+} from 'geotiff';
 import {
   Projection,
   get as getCachedProjection,
@@ -17,8 +22,9 @@ import {fromCode as unitsFromCode} from '../proj/Units.js';
 
 /**
  * @typedef {Object} SourceInfo
- * @property {string} url URL for the source GeoTIFF.
- * @property {Array<string>} [overviews] List of any overview URLs.
+ * @property {string} [url] URL for the source GeoTIFF.
+ * @property {Array<string>} [overviews] List of any overview URLs, only applies if the url parameter is given.
+ * @property {Blob} [blob] Blob containing the source GeoTIFF. `blob` and `url` are mutually exclusive.
  * @property {number} [min=0] The minimum source data value.  Rendered values are scaled from 0 to 1 based on
  * the configured min and max.  If not provided and raster statistics are available, those will be used instead.
  * If neither are available, the minimum for the data type will be used.  To disable this behavior, set
@@ -189,7 +195,9 @@ function getImagesForTIFF(tiff) {
  */
 function getImagesForSource(source, options) {
   let request;
-  if (source.overviews) {
+  if (source.blob) {
+    request = tiffFromBlob(source.blob);
+  } else if (source.overviews) {
     request = tiffFromUrls(source.url, source.overviews, options);
   } else {
     request = tiffFromUrl(source.url, options);
diff --git a/test/browser/spec/ol/source/GeoTIFF.test.js b/test/browser/spec/ol/source/GeoTIFF.test.js
index 778f965956..699bd13201 100644
--- a/test/browser/spec/ol/source/GeoTIFF.test.js
+++ b/test/browser/spec/ol/source/GeoTIFF.test.js
@@ -80,6 +80,25 @@ describe('ol/source/GeoTIFF', function () {
         tile.load();
       });
     });
+
+    it('loads from blob', (done) => {
+      fetch('spec/ol/source/images/0-0-0.tif')
+        .then((response) => response.blob())
+        .then((blob) => {
+          const source = new GeoTIFFSource({
+            sources: [{blob: blob}],
+          });
+          source.on('change', () => {
+            const tile = source.getTile(0, 0, 0);
+            source.on('tileloadend', () => {
+              expect(tile.getState()).to.be(TileState.LOADED);
+              expect(tile.getData()).to.be.a(Uint8Array);
+              done();
+            });
+            tile.load();
+          });
+        });
+    });
   });
 
   describe('loading', function () {